Beneath the calm surface of oceans, rivers, and even a glass of milk, tiny plastic particles—almost invisible to the naked eye—have been silently infiltrating ecosystems and our daily lives. Among them, polyamide (PA) microplastics, used widely in textiles, automotive parts, and packaging, pose a particularly stealthy threat. Detecting these microscopic intruders has long been a challenge for scientists, requiring costly and labor-intensive methods. But a new fluorescent dye is shedding light—literally—on these elusive pollutants.
Researchers have developed HMPC, an aggregation-induced emission (AIE)-active dye, that selectively binds to PA microplastics and emits a bright green fluorescence. Unlike traditional techniques, which often rely on expensive spectroscopy equipment or complex pre-treatment processes, HMPC simplifies detection while remaining highly effective across a variety of environments. From seawater and soil to river water and even milk, this dye lights up PA particles without interfering with other types of plastics or natural materials.
The secret behind HMPC’s precision lies in its photophysical behavior. When molecules aggregate, their fluorescence intensifies—a phenomenon known as aggregation-induced emission. By optimizing the dye’s concentration, staining duration, and solvent conditions, the team achieved remarkable selectivity for PA microplastics over ten other plastic types and several non-plastic particles. Mechanistic analyses suggested that HMPC adheres to PA surfaces through adsorption, reinforced by van der Waals forces and hydrogen bonding, allowing the dye to reliably highlight particles of varying sizes and ages under different chemical conditions.
Beyond environmental monitoring, HMPC opens doors to food safety and biological research. The dye successfully identified PA contamination in milk, offering a cost-effective approach for ensuring consumer safety. Moreover, it enabled researchers to track the distribution of PA in living organisms such as zebrafish and brine shrimp, providing insights into how microplastics travel through biological systems and potentially enter the human food chain.
The development of HMPC represents a significant leap toward accessible and precise microplastic detection. Its affordability and ease of use may empower field researchers, environmental agencies, and food safety inspectors alike. By illuminating the otherwise invisible journey of microplastics, HMPC not only helps quantify pollution but also highlights the urgency of addressing a growing environmental and public health concern.
As microplastics continue to spread across the globe, innovative tools like HMPC provide a beacon of clarity—offering scientists the chance to track, understand, and ultimately mitigate one of the most pervasive pollutants of our time.














